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Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential

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By activating GLP1 receptors more strongly and for longer, semaglutide: Slows gastric emptying (food leaves your stomach more slowly)

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Indeed, UBX0101 treatment on aged mice with post-traumatic OA after surgery reduces the presence of senescent cells, improves articular cartilage, and upregulates the expression of genes involved in new cartilage growth 25